how long do venofer side effects last

Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. It belongs to a class of medications called iron replacement products. One study of just under 5000 HRT users found that 43% were affected. 2023 Medicine.com All rights reserved. Infusions should be administered over at least 15 minutes. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. Examples of these side effects include dizziness and nausea. intense abdominal pain. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. You can also write a reminder on your calendar. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. experience severe side effects, please seek medical attention right away and notify the ordering physician. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Your doctor will do laboratory tests to monitor your response. Call your doctor for medical advice about side effects. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. <> Its caused by your body not having enough iron, which is needed to make hemoglobin. This is not a complete list of possible side effects. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. There have also been reports of serious allergic reactions to Venofer. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Side effectswill last a very long time if the cause of them is not resolved. administered at your doctors office or an infusion center. Venofer (iron sucrose) Uses, Dosage, Side Effects - Drugs.com You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. For people with certain medical implants, such as pacemakers, an MRI may pose an . This includes your doctors, nurses, pharmacists, and dentists. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . PDF Protocol for the use of Intravenous Iron Sucrose (Venofer Iron is an essential nutrient needed to maintain energy levels and keep you healthy. I used to get a different type but my . Headache. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. Not all possible drug interactions are listed here. Follow all instructions closely. The following information describes dosages that are commonly used or recommended. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. Effectiveness of Injectafer compared with iron thats taken by mouth. (A medication class describes a group of drugs that work in the same way.). Venofer may cause significant hypotension (decreased blood pressure). (For more information on Venofer, see the Injectafer vs. Venofer section above). The Injectafer dosage your doctor prescribes will depend on your body weight. Should I avoid certain foods while taking Venofer Vial? Venofer (iron sucrose) injection, USP | Patient Site Is the ketogenic diet right for autoimmune conditions? Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. With anemia, you have a low level of red blood cells (RBCs) in your body. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Storage Condition Store in a cool and dry place protected from light. Following an LSD trip, users may experience a sort of 'comedown.'. * This is a partial list of mild side effects from Injectafer. How is Venofer (iron sucrose) given? Learn more about these, as well as the symptoms, diagnosis, and treatments. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. With IV infusion, the drug is given as a slow drip into your vein over a period of time. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Wellbutrin: Side effects and how to manage them - Medical News Today It's a more immediate treatment than supplements or dietary changes. Details. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. Call your doctor right away if you have serious side effects. MNT is the registered trade mark of Healthline Media. They can give you tips on how to deal with any side effects that may be bothersome. Injectafer comes as a liquid solution inside vials. Some may be a better fit for you than others. Venofer (iron sucrose): Anemia Medication Uses & Side Effects - MedicineNet However, be sure to take the dosage your doctor prescribes for you. Throw away unused or expired drugs. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. During pregnancy, this medication should be used only when clearly needed. What is the latest research on the form of cancer Jimmy Carter has? Some people only need one treatment course of Injectafer. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. Do not start, stop, or change the dosage of any medicines without your doctor's approval. If you notice other effects not listed above, contact your doctor or pharmacist. You may need extra iron because of blood loss during kidney dialysis. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. Together, you and your doctor can develop a treatment plan thats best for you. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Discuss the risks and benefits with your doctor. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. other treatments you receive, you will need to go back for several treatments with Venofer. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. The drug helps increase your hemoglobin level back to a value thats within the normal range. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. dizziness. Iron Sucrose (Intravenous Route) Precautions - Mayo Clinic Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. I had Venofer infusions, 2 rounds now in the span of three years. Iron infusion: Uses, benefits, and what to expect - Medical News Today This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. In Canada - Call your doctor for medical advice about side effects. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. In the first group, some people continued taking iron by mouth, while other people took Injectafer. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. Is Venofer Safe in Breastfeeding - Drlact.com What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Boxed warnings alert doctors and patients about drug effects that may be dangerous. Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Other drugs are available that can treat iron deficiency anemia (IDA). muscle pain. Common and Rare Side Effects for Venofer Vial - WebMD This gives a total cumulative dose of 1,500 mg of Injectafer. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Venofer is for use in adults and children at least 2 years old. You may also report side effects at https://www.fda.gov/medwatch. But you kidneys need iron in order to make EPO. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. You may also need to monitor your blood pressure at home. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; reese0809 1 yr. ago. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Potential injection site discoloration has happened. Learn about the causes, symptoms, diagnosis, and treatment of this. Below are examples of these side effects. It belongs to a class of medications known as iron replacement products. Mental healthdisorders like depression may requireantidepressantsto treat. Serious side effects from Injectafer arent common, but they can occur. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. And this person had gotten their first dose of the drug without having an allergic reaction. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). % Learn about uses, cost, how it works, and more. <> No, you most likely wont take Injectafer long term. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. If you have symptoms of a low phosphorus level, call your doctor. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Injectafer is a brand-name prescription drug. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. Very bad and sometimes deadly allergic side effects have rarely happened. Venofer (iron sucrose) Uses, Dosage, Side Effects, FAQ - MedicinesFAQ This survey is being conducted by the WebMD marketing sciences department. generalized weakness. Learn how to store and discard medical supplies safely. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. endobj Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). Once inside your body, ferric carboxymaltose releases iron into your system. Always review your medical history with the treatingphysician. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Venofer is not for treating other forms of anemia not caused by iron deficiency. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. weakness. Use Venofer as ordered by your doctor. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. Do not start, stop, or change the dose of any drug without checking with your doctor. Talk with the doctor. I can't take oral supplements because they cause horrible debilitating Constipation. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. Risks of Hypophosphatemia Following Intravenous Iron Injectafer helps to treat IDA by providing an iron infusion directly into your body. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. Things to remember when you fill your prescription. Before using, check this product visually for particles or discoloration. Venofer pregnancy and breastfeeding warnings. There are currently no generic forms of either drug. Then your body uses that iron to make hemoglobin and RBCs. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . Understanding what thoseside effectsare can lead to a strategy to prevent them. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Do not share your drugs with others and do not take anyone else's drugs. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Iron infusion benefits. For example: Say you weigh 105 pounds (about 48 kilograms). Tell your doctor about the allergy and what signs you had. Your doctor will determine the best dosage to fit your needs. pain or burning at the injection site. Change in taste. But if they become more severe or dont go away, talk with your doctor or pharmacist. If these effects continue or worsen, tell your doctor. Venofer: Uses, Price, Dosage, Side Effects, Substitute, Buy Online While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Heart failure: Could a low sodium diet sometimes do more harm than good? Its responsible for carrying oxygen throughout your body. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. People from different ethnic backgrounds process medications differently. Version: 7.01. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. (A medication class is a group of medications that work in a similar way.). Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. These side effects can range from being mild to severe. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. endobj If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. Weight changes may be due to symptoms of anemia improving. Heres some detail on certain side effects this drug may cause. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. These effects typically last between 7 and 11 hours. There are currently no generic forms of either drug. And this can affect how well those parts of your body are able to work. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Some drugs may have another patient information leaflet. This may be helped by giving the medication more slowly or at a lower dose. Here are answers to some frequently asked questions about Injectafer. treatment schedule in further detail. These changes could help improve your anemia on a long-term basis. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. I had my first infusion of 1gm 10 days ago. What Is the Cost of Whole Genome Sequencing (WGS)? In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. These are not all of the side effects that may occur. Are there side effects from an MRI? - Coalitionbrewing.com Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. 2 0 obj This means you would get two Injectafer doses of 720 mg each. The drug helps increase your hemoglobin level back to a value thats within the normal range. Its not currently available in generic form. Iron sucrose can also be mixed in a. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. Call your doctor for medical advice about side effects. Red Tide in Florida: What You Need to Know | OutCoast.com They can tell you about other medications that may work well for you. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Injectafer is approved to treat iron deficiency anemia (IDA). Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Yes, in some cases it may. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. Learn more about the types of tests and treatment. With slow IV injection, the drug is given as a single, slow injection into your vein. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. A healthcare provider will give you this injection. %PDF-1.3 You may report side effects to the FDA at 1-800-332-1088. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. In the US - Call your doctor for medical advice about side effects. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Side effects are uncomfortable reactions to medications or drugs. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. (Hemoglobin is a protein thats found in red blood cells.). Many people using this medication do not have serious side effects. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. Iron Infusion: Benefits, Side Effects, and What to Expect - Healthline However, consuming large amounts of alcohol can actually cause anemia in some people. Venofer (Iron Sucrose (Injection)) - Side Effects, Interactions, Uses In the second group, some people switched from taking iron by mouth to taking Injectafer. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). . Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Their medical staff can help you set up another time to receive your Injectafer dose. Terminal half-life ranges from 7 to 12 hours. If you notice any changes to your normal blood pressure, call your doctor right away. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. Most people do not know how long theirside effectswill last until they go through them. You should always consult your doctor or another healthcare professional before taking any medication. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Here we look at how Injectafer and Feraheme are alike and different. How Long Do Immunotherapy Side Effects Last? | Cancer Today If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. This may lead to the person needing a higher dose compared to someone who is muchsmaller. Injectafer (ferric carboxymaltose): Side effects and more Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. No, Injectafer itself wont make you gain weight. All rights reserved. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. (And Injectafer is used to treat IDA.) And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. Its not known how common delayed allergic reaction might be in other people using Injectafer. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. This site is intended for use only by US patients. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug.