Alendronic acid: Uses, Interactions, Mechanism of Action - DrugBank I was prescribed alendronic acid as my DEXA scan showed mildish osteoporosis when I started arimidex. 25 yrs later Ive had a Dexa scan and was told my spine was crumbling and the reading was far worse than the worst possible. Typically, doctors recommend taking osteoporosis medication for 3-5 years. I can't even eat an orange on an empty stomach as it hurts so much. Because of how I tend to react and my blood test results, I thought I would research the new meds first and Im now very pleased that I did. Bisphosphonates are widely used. Im very concerned, like you & so many others, about the side effects of AA which I have just started today! No other cause but the medicine . cant belive my GP gave me these awful tablets . I wonder if it might be something that could help you Ive attached the link to the video below. Hi Judith Ive read your article and the comments with deep interest and concern. On the third dose I took the tablet with a glass of water as usual and as it was 6.30am I decided to take the lurcher I was looking after for a longish walk (as you cant sit down once you had taken the tablet). Took dose 8 yesterday, and so far so good. It works by slowing down the production of the cells that wear down bone (osteoclasts). I was prescribed Alendronic acid because I had been diagnosed with osteopenia back in 2004. Cut out all rubbish from your diet, anything processed or ultra-processed, with tiny treats to stop it being too depressing!
Alendronic acid and teeth - Osteoporosis - Inspire The Royal Osteoporosis Society website is very detailed and useful, with info on exercise you should do more of it which must be weight bearing more so than just walking and promote balance. He says he cured his wifes osteoporosis with the supplementation of boron and he describes the dosage he used in the video. Hey Ive been diagnosed with polymialgia rheumatica too i was prescribed predisolone vit d evacol and now AA Im not having any side effects from it yet but reading all of these comments Im worrying about wether I should take the alendronic acid Ive only taken two up to now but have had no problem with it yet It scares you a bit, Hi I have just been precribed alendronic acid I have not taken it yet as I have had a bad cold. I am taking much more care of myself with exercise an I am totally sugar gluten dairy and alcohol free. A. Doctor said it was a preemptive measure as my left hip was compromised! Again i had another Dexa scan 2 years ago and it was found i have oesteoporosis in the spine which i feel very worried about it. Other symptoms include numbness of the lips which are also dry and sometimes numbness in the chin. Now, the only exercise I get is pottering around my house or gently along my local high street. Brand Names Adrovance, Binosto, Fosamax, Fosamax Plus D, Fosavance Generic Name Alendronic acid DrugBank Accession Number DB00630 Background l feel I am not listened to andn being my age, Im past bothering about. I have been taking them for about 5 weeks. This is a dangerous drug. . So I duly took the AA70, now on third month. This caused the bone to shatter like glass ! The my neck was hurting. I just want to feel better. In 2002 I discovered via the internet that I wasnt desperately ill with an anxiety disorder that only Seroxat could fix. blurred vision, painful or red eyes - these can be signs of swelling of the eye. Sister told the doc she was not taking AA any more, he told her she should take it !. HELP! Thank you. I am 79 and took my first Allendronic tablet last Weds. Im now in my 70s and am doing my best to stay out of a wheelchair. For all patients: Dental practitioners should ask about current or past use of alendronate is for use when you have a high risk of bone fracture due to osteoporosis. When I initially had a bone scan they said Id have another one after three years, Ive never had another one. I have just taken my first one and reading this forum is really interesting. Alendronic acid (bisphosphonate) is a prescription medication used to help your bones stay as strong as possible. I was put on alendronic acid weekly and vitamin d and calcium twice a day . Very useful thread this thanks everyone. I have always looked after my teeth, having paid for a very expensive bridge in 2010 to fill a gap. What an awful position to be in! They began to itch the next day, ( I took my 5th dose of medication) and they were slightly better but I called my doctor and got in To the office Friday. I have taken them for 5+ years and after some research now I discover that the scans can give false readings, i.e. There is a fine balance struck in order to treat symptoms without curing, so your symptoms are only abated when you take drugs, but if you die, then obviously they make no more money. It got better in the day, but flared up at night for a few nights, then resolved. Both risedronic acid and oral alendronic acid have been shown to prevent bone loss when taken daily. This drug is only available for prescription and should be taken with caution. Summary Commonly reported side effects of alendronate include: decreased serum calcium and decreased serum phosphate. The dentist told me there was no possible way the drugs had anything to do with my teeth getting loose, and it was probably just poor dental hygiene, in spite of the fact that I was 56 when these problems STARTED and 63 when I had to give up and pull the last ones. So I have decided that it must be the alendronic acid and I have stopped taking them its making my life unbearable.
bones Archives - The Heart And Brain I too am very healthy woman 67, play golf dance swim walk, so I was upset to be told I had osteoporosis. It's harmful if you suddenly stop taking it without a proper assessment from your healthcare provider. Anything more and pressure builds in my head, I feel lightheaded, my ears ring and my muscles jerk happily away by themselves. I decided to stop. The hygienist cleaned my teeth a few weeks ago. On research I found there has been class law suits against the manufacturer of this drug in Canada. I have an appointment at The Royal Dental Practice, Cromwell Road, Dorchster to have two back teeth removed. I know they say dairy is a good source of calcium but we are not cows and cant absorbe or digest soemthing that is meant for young calves. She sent me to a specialist for a second opinion and he said take it. Which has brought me here as I googled info on this medication. Alendronate works by slowing down the cells that break .
alendronic acid has destroyed my life - hullabaloo.tv Since things improved I kept taking the medication. Im 61 and after a long history of fractures (mostly sports related) and a recent wrist fracture from a fall, I had a DXA scan and have Oseopenia. I am 62. I guess my mouth has changed after a long time and it has not fitted properly for a while. Alendronic acid may put your pregnancy at risk.
She doesnt have osteoporosis but they just put her on these. The optimal length of therapy remains unknown. Im sure they will sound familiar. As far as the AA, its track record shows there have been dental issues in some people. As you age, you will notice changes in your body, such as grayed hair, wrinkles, vision problems, and hearing loss. I could hardly walk with pain all over my body, felt sick, couldnt eat. Warning to anyone who might be taking Alendronic acid 70 ml tablets for osteoporosis ! Lately, i have been feeling quite unwell, and after having had all sorts of health checks I have now come to the conclusion that my strange symptoms might be due to Alendronic acid.
Ask the doctor: How safe are pills for crumbly bones? Then seen a doctor over the pains in my head he asked how long Id been taking alendronic when I told him how long Id on them, he was horrified and reported straight away.They discovered I had broken Vertebrae leaning on my spinal cord.Alendronic should be band. I was told by the hospital after my bone scan that my Osteoporosis was not that bad so Ill see what happens after my next scan Im 73 years old and dont want to feel unwell due to the side effects which if you read about them can be very serious.
Alendronic acid and teeth extraction : r/askdentists - Reddit Ostopenia and had a high risk of a fracture. This condition is common in women after the menopause. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press.. Mayo Clinic on Incontinence - Mayo Clinic Press Mayo Clinic on Incontinence; NEW - The Essential Diabetes Book - Mayo Clinic Press NEW - The Essential Diabetes Book; NEW - Ending the Opioid Crisis - Mayo Clinic Press NEW - Ending the Opioid Crisis The method comprises the steps of reacting a compound of formula I with H 3 PO 3 wherein R is an imido group and R 1 is selected from the group consisting of chloro, bromo, iodo, fluoro, hydroxy, amino, OR 2 or OC(O)R 2 , wherein R 2 is C 1 -C 12 alkyl, C 1 -C 12 cycloalkyl or C 1 -C 12 aryl; and then reacting the . She decided to come off the Alendronic AcidShe really has gone downhill. The side effects are horrific. Please check with your doctor before stopping taking alendronic acid and switching to alternative treatments. Hi Rowena. Any advice would be greatly appreciated. Since taking alendronic, I have had difficulty in running and doing all the workout I was doing. Its essential to take your dose while your body is upright. I began to take as prescribed and do not have any problems until 6 days after my 4 th dose, I was awakened in the night with uncomfortable, aching wrists. I was such an idiot for believing in this drug! As a consequence, my Dr prescribed Alendronic Acid 70mg. Following breast cancer they want me to take Aromatase Inhibitor along with a Biphosphonate Clondronate or Zolendronic so my question to everyone out there will these other biphosphonates result in similar pain? Alendronate is the drug we know as Fosamax. Muscle pain all the time hot sweats but put that down to menapause each time going to doctors about my symptoms only to be told the good will out way the bad Iike hell did it only at the end of july I was walking minding my own business with friends in torquay on holiday 1 day into my holiday I was crossing the road &my leg broke in front of me so I sustained a femur fracture due to AA which has been confirmed twice it was the AA that has caused this I have now come off them my sweats have stopped along with the others symptoms all stopped all off most I put down to a long menapause.
Alendronic acid Versus Arthritis The doctor put me on ADCAL D3 and alendronic. There has to be a better way. It knocked me out so I stopped it. My story begins in May 2014 when I was 72 and took the first once a week dose of one tablet with a glass of water. With this condition, your bones become thin and weak, and break easily.
Possible Interactions with: Calcium | Complementary and Alternative Engineered Nanomedicine with Alendronic Acid Corona Improves - PubMed Wait for at least 30 minutes after taking the drug. A blood test followed and the inflammation was evident in the test, but I did not test positive for RA which I was worried about. Energice is a vitamin infused Premium Isotonic ice bar scientifically formulated with Electrolytes, B Vitamins (B3, B5, B6, B12) and Potassium. She suggested maybe I stop taking the AS but I already had. oscar the grouch eyebrows. I was given alendronic acid tablets, one a week after had fall off my bike swerving to miss a coke can someone dropped and fractured my pelvis. I started reading this because after being diagnosed with breast cancer part of my ongoing treatment is Letrozole plus Alendronic Acid. My wrists were swollen, aching. My walking is less than a quarter of what it was, but that could be due to a herinated disc. I had settled on a very low dose of Seroxat, enough to keep withdrawal at bay but not enough to have a therapeutic effect, because I didnt need one. Reading all above, i think i will put myself on a little break, just to see if there is a difference in my condition overall. Until recently I only took my Thyroid med.
Side effects associated with alendronic acid | RxISK She was given physiowhat a mistake that was.After fighting to get her x rayed, the doctor phoned her and said that I was right and she needed a hip replacement, her hips had crumbled away. I asked how we would know if it wasnt working, and his reply was that it would be having an effect on my bones after six months and the next scan results would indicate an increased bone density, or not. How Alendronic Acid works Alendronic Acid is a bisphosphonate. Hi just wondering how your getting on with the alendrolic acid? I was tested for gluten intolerance and was told I was gluten intolerant in 2011. The medicine your doctor has advised you to take, alendronic acid, is one of the bisphosphonates and is given to strengthen fragile bones. My worry at the moment is that I need a new crown in my teeth and do not know if this permitted and if I go ahead will it affect the health of my gums. What is soil degradation in agriculture? Itching in my left shoulder/arm, have gained weight and my mood has changed. I was prescribed AA 70mg one per week and took the first dose on Saturday which gave me such severe joint and muscle pain all over my body within 24-36 hours that I was barely able to walk or stand. Food, mineral water, and other beverages may interrupt your body from absorbing the medicine.
Experiences with Alendronic acid | HealthUnlocked Dont freeze it but keep it at room temperature between 15-30C. Started on Fosamax l6 years ago. Despite the doctors assurances that it wasnt addictive, I became addicted. There is a phrase called the patient financial profile which is the profit made from an illness or disease or condition without the patient either getting cured or dying.
Alendronic Acid Produces Greater Effects Than Risedronic Acid - Medscape I drank 2 cups of coffee. She doesnt have osteoporosis. My specialist came back to me a month ago to tell me I should take AA from now on so I started taking the weekly pill 4 weeks ago.
Alendronic acid monohydrate | C4H15NO8P2 - PubChem Also take two drugs for cholesterol and statins i rattle !! My rheumatologist prescribed AS but I dalayed taking as I had lots of dental work to be done. Having read & researched online information regarding side effects I accepted that I needed to take the Prednisolone but was not comfortable with ADCAL 3D + Alendronic Acid & especially since my Vitamin D level was so good but was advised to take them taking into account my age of 73years. He arranged for me to have an MRI and EEG tests, but his opinion was that Seroxat was the likely culprit as he had never seen anything like this before. Has anyone has this done ? If you are taking this tablet once a week . I have had to keep off coffee, fruit and anything acidic for months, I even tried gaviscon which made me feel sick and had a bloated stomach for 2 hours. Took dose 7, and on and off right hip aches, but now radiating to thigh. Just had to reply to your post! As I sat up from the bed my head started to pound. That was the last tablet I took of that drug.
Alendronate (Oral Route) Side Effects - Mayo Clinic I think I will investigate more about Boron like the reviewer above.
Alendronic acid produces greater effects than risedronic acid - PubMed I was told I had osteoporosis in 2004 and was put on Fosamax for about 6 months after which I was switched to Actonel. I also have arthritis in my thumbs. Alendronic acid has been studied in a small number of patients with osteogenesis imperfecta under 18 years of age.
1 Recommendations | Bisphosphonates for treating osteoporosis What is Alendronic acid 70mg tablets used for? I am going down the route of continuing my swimming with a healthy diet some weight bearing Zumba step exercises. Both. In April 2010 I went back to my gym routine, and within a few weeks the second jerking episode occurred. Maybe tomorrow I will get better direction from the physician. GP is arranging for a bone scan . In addition, you should cut down on your alcohol intake, stop smoking, do strength training and supplement your body with calcium and vitamin D3, K2, and magnesium regularly. When my doctor told me emphatically that I couldnt build my bones with diet and exercise alone, I reluctantly said ok, but I want to take strontium. Now I am not sure what to do. After reading the comments I will not be taking it again. As soon as I told the duty doctor it was a possible drug clash, I sensed he immediately lost interest. It begins as minor dental problems and can escalate to permanent jaw damage. I also had pain/soreness behind the eyes and a niggling headache for 48 hours. I attributed this to having a 12 hour car ride and driving 6 out of 12 hours. But, because you naturally produce vitamin D3, your doctor might not recommend you take supplements unless you have a deficiency. Gave up Alendronic Acid recently after a random chat with a friend! Without the support of new bone tissues, your bones become more porous and fragile, making you prone to bone fractures. Burning chest pain, sore throat and pains all over. Hello I am 66 and like many of you am hating taking this drug, I had breast cancer 4 years ago,so am still taking Anastrosil as it was Hormone related,which in turn apparantly helped causing bone density loss, so ws then diagnosed with osteopenia I read the leaflet and decided to google. For a once health, fit woman shes a frail person now who cant walk and has bladder/stomach problems. It hurts to walk on my feet. My idea of a short walk had always been an hour and a half in the woods with my dog my favourite footwear was my walking boots. All Rights Reserved. Withdrawal was so extreme that the longest I ever lasted off the drug was seven weeks, the worst of my life. It will slow down the breakdown of bones and support the faster growth of new bones in your body. Thank you for your comment. I have also been taking Adcal tablets for years. Where do you live Jane hope you dont mind me asking. Singing, to my deep distress, is now out of the question, along with all the other active things I loved to do. I do have quite a high reading of osteoporosos but I feel I need to know what it really does to the body. who told me it could be one of many things. My recent BMD test shows i have esteoporosis. Next morning extreme pain in my back and kidney area. She used to get upset stomach the day & day after taking them. Does anyone know the scientific evidence for Alendronic acid and what it does to the body that makes so many people feel achy and dizzy? I do wonder if all of this is as a result of being on Seroxat for so long. Dodgy tummy, acid reflux, sleep problems and hair loss. Your dentist will have heard of it and will ensure that you have any treatment done before you start. Then one day my body turned to chaos. Due to Covid I only had a telephone consult with an Endocrinologist. Im going to stop taking Alendronic acid. The whole remit of Western medicine is to treat symptoms without curing, so that long term profits can be made. At which point he told me that NICE guidelines indicated that he had to prescribe alendronic acid, and he could only move me to a different drug if it didnt work. Given ENEMA which got things moving but still having problems so was referred for COLONOSCOPY!! Also taking into account that I have & still do.Lead a very active & healthy lifestyle! 2 years. Newsletter archive, Data Based Medicine Global Ltd. It is relevant at this point to say that my sister lives in Australia which has different prescribing criteria. It was becoming clear to me at this point that activity brought on my symptoms, and at that time it was extreme activity a session at the gym, a long bike ride, a strenuous walk. Then, they will assess if youll have to continue taking it or take a break from it by stopping the medication completely. Same here. You could suffer from much weaker bones and severe fractures without proper care. I also broke my hip, which made it even more difficult to do anything at all. Thank you.
Drug treatments to protect your bones | Macmillan Cancer Support thanks for this site. Hello Jane,
How Alendronic Acid Destroyed My Life - Meds Safety This is fascinating.
The Pembrokeshire woman living in fear because of a drug - ITV News I had heard of necrosis in the bones before and she had all the symptoms. Its 2.35am here in Kent & I am terrified about what 2moro will bring if I am forced to use AA.
Can't take another alendronic acid - Breast Cancer Now Forum Anyhow, if anyone knows what whip lash feels like, this is worse. I would like to take an alternative to alendronic acid wuth some exercises for the spine.
PDF NHS Trust How to take Alendronic Acid and Calcium and Vitamin D - OUH If you were prescribed to take 10 mg of alendronic acid, swallow one whole tablet daily. Meds Safety . judy. Alendronic acid | C4H13NO7P2 | CID 2088 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities . 74, fractured hip. However Im convinced that its the AA tablet and am very scared to take another! She is having pain in her legs, hips and groin. Its essential to take calcium supplements and vitamin D3 at least 2-4 hours before your first dose of alendronic acid. If I apply pressure to my temples, my headache lessens. I took it on Tuesday. Do not take this drug if you have mild to severe kidney problems. If youre unsure of your tap water, you can boil it for 1-3 minutes and cool it down before drinking. It is commonly prescribed to treat patients with bone issues like osteoporosis and Pagets disease. After reading about it I returned the box of tabs unused. As a follow up to my earlier post, on Feb 21st 2021, I am still experiencing side effects as a result of the ingestion of 1 biphosphonate Alendronic Acid 70g tablet on Sunday Feb 2nd. so I was looking up side affects of AA which brought me to this site and I dont like what I am reading, so I am going to ring my doctors and have a talk my gut feeling is not to take them. the pain in my muscles and bones is unbearable, chills, last I had night sweat, my stomach was bloated, acid reflex and the headache along with my jaw ache wont go away. Delighted to report Tum is behaving much better since giving up just hoping the other side effects ( Jaw and Teeth) dont show up unexpected! Never in my life have I read as many horror stories and am dumbfounded that medication like this is still being prescribed. Im considering ringing the hospital myself to see if I can have one done. But no issue with my teeth. Already taking Adcal D3 and steroids. I have been taking A.A for about 9/10 months. It may put you at risk of jaw bone damage. Fillings etc are fine but anything more invasive can be really very difficult to manage it. Thanks.
alendronic acid has destroyed my life - v1.tricityltd.com Took my 1st AA 2 days ago, since then Ive had constant stomachache, feel exhausted, and tired, and shivering. how to prove negative lateral flow test. What an awful time you are having my sympathy goes out to you. Your body naturally breaks down old bones and replaces them with new bone tissues to support your skeletal system throughout life. I am posting this to try and help other , from being in the same situation that I have been in for last 5 months . My body jerked violently and out of control for hours. I quit often find that some of the drugs my doctor has given me gives me bad reactions. Hi,all these comments are really helping me to decide not to take anymore Alendronic Acid,I had my Dexa scan September 2017 and was diognosed with Osteoporosis and prescribed AA and Cal D3. I will make sure I get it. Are we not sentient beingsthey are not the be all and end all. Please talk to your doctor about this. By this time my body was still, so I went home feeling scared and utterly distraught. where do I go from here, the last thing I want is dentures !! Land degradation also has serious knock-on effects for humans, such as malnutrition, disease, forced migration, cultural damage, and even war. I am interested about the post that said you should only really take for 2 years does anyone else have info on this. Shingles 6 months ago and Dr. says this is result of shingles. alendronic acid has destroyed my life It should be taken as soon as you get out of bed in the morning and at least 30 minutes before any food, beverage, or other medicines. I think she must have dislodged it, I also have something called GCA which can affect your jaw so I cant say which or if either has caused the problem. My GP told me to take alendronic acid with the calcium and vit D tabs 5 or so years ago (in my mid 40s), after a DEXA scan showed I had mild osteoporosis already. There are 8,218 reported reactions, bear in mind many dont report the side effects to the Yellow Card Scheme.
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